Level of Study

Bachelor degree

Workload

Total hours: 144

Contact hours: 80

Prerequisites

General and Inorganic Chemistry

Course Objectives

The students will:

• recognize main functional groups of organic compounds and predict their chemical properties, taking into account the type of chemical bond connectivity, hybridization state, and stereochemistry;
• identify reaction mechanisms for chemical processes with formation of intermediate free radicals, nucleophilic, and electrophilic agents; predict major product in reactions with participation of organic compounds;
• define the reagent nature as free radical, nucleophilic, or electrophilic, and use this knowledge to perform a synthesis of organic compounds belonging to main classes;
• demonstrate laboratory skills, including safety, handling and disposal of organic compounds; experimental procedures such as isolation, purification and structure identification of reaction products obtained; use of laboratory equipment; and writing experimental reports according to the style adopted for scientific publications.

Learning Outcomes

Upon completion of this module the students will be able to

• develop an optimum procedure for obtaining specified organic compounds from commercially available initial substances;
• make identification of organic compounds on the base of their nuclear magnetic resonance (NMR), infra-red (IR), and mass spectra;
• predict direction of a chemical processes with a participation of organic compounds regarding possible reaction mechanisms;
• suggest methods of isolation and identification of synthesized organic compounds belonging to different classes.

Syllabus

Introduction. Classification of organic compounds.
Classification of organic reactions and reagents.
Alkanes, alkenes, and alkynes: obtaining and chemical properties.
Arenes: aromaticity, structure, isomerism, nomenclature, and obtaining.
Orientation rules in the aromatic ring. Electronic effects in organic molecules.
Halogen derivatives of hydrocarbons: obtaining and properties.
Alcohols and phenols: obtaining and chemical properties.
Carbonyl compounds: aldehydes and ketones.
Carboxylic acids and their derivatives.
Nitrogen-containing compounds: nitroarenes and nitroalkanes, amines.

Labs

Simple distillation of organic solvents.
Thin-layer chromatography and its application for reaction control.
Synthesis of propylene.
Purification of p-nitrobromobenzene.
Synthesis of isopropyl bromide.

Assessment

Quiz: Classification of organic reactions.
Quiz: Hydrocarbons.
Quiz: Halogen derivatives.
Quiz: Oxygen-containing compounds.
Quiz: Nitrogen-containing compounds.
Final assessment: Exam