Effects of ionizing radiation: radiation effect on molecular, cell, tissue and body level. Somatic and intrinsic, stochastic and non-stochastic effects of irradiation.
Norms and regulations of radiation safety of ICRP and UN CEAR: Problem of small doses; genetics effects of ionizing radiation. Radiation cancer formation. Problem of radiation life reduction. Linear nonthreshold dependence dose-effect. Hormesis. Radiation risk..
Norms and regulations of radiation safety in Russian Federation.
Practice
General principles of dosimetry. Exposure and absorption doses.
General biological effects of radiation, tissue weighting factor, equivalent dose, linear energy transfer.
Definition of radiobiological parameters of cell structures based on multi target model of cell survivability.
Oxygen influence on survivability of cell structures , oxygen effect, coefficient of oxygen enhancement – classical definition and function of dose.
Laboratory
Dosimetric planning for radiation safety of patients at external gamma therapy.
Ways of generating safe radiation fields in external gamma therapy.
Dosimetric planning for radiation safety of patients at intracavitary gamma-therapy.
Dosimetric planning for radiation safety of patients at neutron external therapy.
Dosimetric planning for radiation safety of patients at external neutron-gamma therapy.
History of developing safe planning methods of beam therapy.
Dosimetry of ionizing radiation as basics for dose planning and beam therapy: basic processes on beam interaction with media, photon’s energy transfer in media, theory of Bragg-Gray, Ionizing chambers, characteristics of dosimetry in beam therpay.
Therapy using photons: planning beam therapy with x-ray apparatus, therapy using Co-60, simulation of absorption dose distribution from Co-60 in tissue equivalent media, calculation of dose distribution with multi field irradiation, ways of taking into account inhomogeneity in tissue, optimization of fractioning regime of a dose, spatial optimization of absorption dose distribution, intracavitary gamma therapy, dose calculation in static and rotation regimes, beam therapy using accelerators, model NSD, computer simulation of dose distribution.
Therapy using electrons: principles of calculating dose distribution in patient’s body in electron therapy, characteristics of electron field generating for beam therapy, representation of electron radiation fields in isodose lines, intracavitary electron therapy with external gamma-therapy, computer simulation of dose distribution in intracavitary electron therapy with external gamma-therapy.
Therapy using neutrons: neutron sources for neutron therapy, characteristics of neutron dosimetry in tissue-equivalent media, distribution of neutron doses in tissue equivalent media, computer simulation and planning neutron and gamma-neutron therapy, area of neutron therapy application.
Technologies of producing radiopharmaceuticals 6 kreds
Lectures and Practice
Using radionuclides and radiopharmaceuticals in medicine. Choosing radionuclides for medical and biological investigations.
General principles of obtaining images using radioisotopes. Planar, dynamic and tomographic scintigraphy. Devices for radiodiagnostics. Gamma camera and positron emission tomograph.
Producing radionuclides in nuclear reactions.
Producing radionuclides using cyclotron.
Producing radionuclides and radiopharmaceuticals using nuclear reactor.
Methods of quality inspection of radiopharmaceuticals.
General and Inorganic Chemistry, Organic Chemistry
Course Objectives
1. Predict reaction paths for general organic synthesis methods. 2. Choose reagents and conditions for functional group transformations. 3. Design synthesis schemes for organic compounds with several functional groups starting from simple molecules. 4. Build experimental set-ups and carry out basic chemical operations in organic chemistry lab.
Learning Outcomes
After completing the course the student will be able to: – design an experimental procedure for the synthesis of organic compounds; purify reaction products and determine their properties; – predict reaction mechanisms for basic transformations of organic compounds; – calculate the amounts of reagents for a given organic reaction, calculate product yield; – draw structures of stereoisomers, identify the stereogenic center and assign the absolute configuration for a given molecule.
1. Smith V. Foundations of modern organic synthesis, 2012. http://e.lanbook.com/books/element.php?pl1_id=3171 2. March, Jerry Advanced organic chemistry : Reactions, mechanisms, and structure / J. March. — 7-th ed.. — New York: John Wiley & Sons, 2013. — 1495 p.
Basic technologies of inorganic substances and materials
Level of study
Master Degree
Workload
ECTS: 3 Total Hours: 96 Contact Hours: 32
Lectures: 16
Labs: 0
Seminars: 16
Course Code
Semester
Winter
Prerequisites
Professional English language. Processes and devices of chemical technology The main directions of the chemical technology of inorganic substances
Course Objectives
Formation of the ability to operate and service modern high-tech production of inorganic substances and materials, to correspond the environmental protection requirements and the rules of industrial safety.
Learning Outcomes
Master students will be able to: discuss the basic technologies of inorganic substances; select the raw materials and technology for producing inorganic substances; control the quality of raw materials and products; apply the professional knowledge and skills in the field of chemical technology of inorganic substances and materials; predict the environmental impact of the technological scheme of inorganic material manufacturing.
Syllabus
• Classification of the main inorganic materials. • Catalysts in inorganic materials technology. • Production of technological gases. • Production of synthetic ammonia. • Production of inorganic acids (nitric, sulfuric, phosphorous).
Labs
Projects
• Modern state and trend in the global production of inorganic materials. • The raw material in the technology of inorganic substances. • Composition of catalysts for the production of inorganic substances and functions of their components (catalytically active component, support, promoter, inhibitor, poison). • Global trends in the production of process gases. • Features of technologies of inorganic compounds (synthetic ammonia, nitric acid, sulfuric acid) in different countries.
Assessment
Credit Test
Resources
1. Hein, Morris. Introduction to General, Organic, and Biochemistry / M. Hein, S. Pattison, S. Arena. – 10th. – Hoboken: John Wiley & Sons, Inc., 2011. – 480 p. 2. Miles F.D. Nitric Acid: Manufacture and Uses. – Oxford University Press. 1961. – 185 p. 3. Elemental Sulfur and Sulfur-Rich Compounds l / editor R. Steudel. – Berlin: Springer-Verlag, 2003. – 202 p. 4. Louie D.K., Eng P. Handbook of Sulphuric Acid Manufacturing, 2 nd edition. 2008. – 1488 p. 5. Appl M. Ammonia: Principles and Industrial Practice. – WILEY-VCH Verlag GmbH. 1999. 6. Ashar N.G., Golwalkar K.R., A Practical Guide to the Manufacture of Sulfuric Acid, Oleums, and Sulfonating Agents. 2013. – 146 p. 7. Ross J.R.H. Heterogeneous Catalysis: Fundamentals and Applications. – Elsevier. 2011. – 232 p. 8. Appl M. Ammonia: Principles and Industrial Practice. – WILEY-VCH Verlag GmbH. 1999. 9. Evangelou V. P. Pyrite Oxidation and its Control. CRC Press, 1995. – 293 p. 10. Louie D.K., Eng P. Handbook of Sulphuric Acid Manufacturing, 2-nd edition. 2008. – 1488 p. 11. King M., Moats M., Davenport W.G.I. Sulfuric Acid Manufacture. Analysis, Control and Optimization. – Elsevier. 2013. – 608 p. 12. Marisa Callio, Ana Gimeno, David Perry, Rafael Seiz. English for Mechanical and Chemical Engineering. – Reproval S.L. 2001. – 132 p. 13. Gilmour R. Phosphoric Acid: Purification, Uses, Technology, and Economics. – CRC Press. 2013. – 354 p. Internet-resources 1. Sulphuric acid. The contact process / https://www.youtube.com/watch?v=BkdjR5DZBl0 2. Ammonia Synthesis / https://www.youtube.com/watch?v=00Tka0ytAQk
This module gives an opportunity to review the variety of up-to-date technologies in mechanical engineering, to focus on widespread types of equipment and progressive operation methods, and to acquire experience in equipment operating. The course is aimed at students training in: • service and operation of the up-to-date mechanical engineering equipment and processes; • industrial engineering and design activity in the field of mechanical engineering; • self-study and development of new professional knowledge and abilities.
Learning Outcomes
Having successfully completed this module, you will know: • technology of materials and products manufacture, • physical bases of materials processing by pressure, cutting, casting and welding, • variety and design of equipment, fitting and tools for materials processing. Having successfully completed this module, you will be able to: • choose a method of material processing for the specific purpose, • specify parameters of processing schedule, • reveal advantages and disadvantages of new technological processes, • search for the scientific and technical information in the field of construction materials engineering. Having successfully completed this module, you will acquire: • experience in metal-cutting equipment operating, • skills in moulding and casting design, • experience in revealing of processing defects.
Syllabus
1. Bases of ferrous metallurgy 2. Metal forming 3. Foundry production 4. Welding manufacture 5. Metal cutting (machining)
Labs
1. Equipment and technology of forging 2. Sand casting moulds manufacture 3. Special methods of casting 4. Casting design 5. Manual arc welding 6. Resistance welding 7. Metal processing by cutting 8. Machining on lathes 9. Milling and planning machine tools
1. Predict reaction paths for general organic synthesis methods. 2. Choose reagents and conditions for functional group transformations. 3. Design synthesis schemes for organic compounds with several functional groups starting from simple molecules. 4. Build experimental set-ups and carry out basic chemical operations in organic chemistry lab.
Learning Outcomes
After completing the course the student will have knowledge about: − structure and basic content of the course, as well as the interconnection of the course parts between each other; − basic methods and techniques for the study of structure and elemental composition of nanomaterials and articles on their base; − physical principles lying in the basis of study methods of nanomaterials and articles on their base, their advantages and limitations;. Skills: − to classify modern methods and techniques of the study of structure and elemental composition of nanomaterials on their purpose and technical characteristics; − to define, to systemize and to obtain necessary data in the field of his activity with the use of newest study methods and fundamental knowledge; − to collect, to treat and to systemize scientific and technical information on the studied discipline; Experience: - methods of preparation of data for creating reviews, reports and presentations on scientific and technical activity; - methods of organization of Internet resources for collecting interdisciplinary knowledge in the field of modern study methods of nanomaterials, qualified generalization of scientific data; - ability to elaborate, to confirm scientifically and methodologically the schemes of optimal complex attestation of realization products of high technology processes of nanomaterials manufacturing.
Syllabus
1. General notions on probe methods for studying nanomaterials structure 2. Physic bases of scanning tunnel microscopy microscopy. 3. Physic bases of atomic force microscopy. 4. Physical bases of electric force (EFM). 5 Physical bases of magnetic force (MFM). 6. Physical bases of near-field optical microscopy (NFOM). 7. Application of probe methods to the study of nanomaterials structure. 8. Presentation of the library research work
Labs
Projects
Assessment
Exam
Resources
1. Mironov, V.L. (2005). The fundamentals of scanning probe microscopy. Мoscow, Tekhnosfera. 2. Nevolin, V.K. (1996). The fundamentals of tunneling probe nanotechology: tutorial. Мoscow, MGIET (TU). 3. Rakov, S.A.. (2001). Scanning probe microscopy of semiconductor materials and nanostructures. S.-Petersburg, Nauka. 4. Meyer, E., Hug, H. J., & Bennewitz, R. (2013). Scanning probe microscopy: the lab on a tip. Springer Science & Business Media.
Hydromechanical and heat transfer processes in chemical technology
Level of study
Master Degree
Workload
ECTS: 4 Total Hours: 60 Contact Hours: 60
Lectures: 0
Labs: 0
Seminars: 60
Course Code
Semester
Winter
Prerequisites
Professional English language. Higher Mathematics. Fundamentals of mechanics.
Course Objectives
Develop the ability to understand physico-chemical nature of the processes and to know the basic laws of chemical processes occurrence in complex production-technological activity. To know the basic design heat of equipment used in chemical industries. Develop the ability to perform the necessary physico-chemical and thermodynamic calculations of basic parameters of chemical-technological processes on the basis of methods, processes and apparatuses of chemical technology. The formation of creative thinking, the unification of fundamental knowledge of the basic laws and methods of calculation chemical processes and physico-chemical researches, with subsequent processing and analysis of research results. Formation of skills of independent theoretical and experimental research in the area of fundamental processes of chemical productions and chemical Cybernetics in the field of machines and apparatuses of chemical productions.
Learning Outcomes
Formation of knowledge about the basic processes of heat transfer and hydromechanics. Realization in chemical technology. Training to skills of thematic information search. Formation of the basic skills of calculation of heat transfer processes in chemical engineering. Formation of skills of calculation of hydromechanical parameters of devices and communications in chemical engineering.
Syllabus
• Basic laws of processes and general principles of calculating devices of chemical technologies – 15 hours per semester. • Hydromechanical processes and devices – 15 hours per semester. • Separation of heterogeneous systems – 5 hours per semester. • Heat exchange processes and apparatus – 25 hours per semester.
Labs
Projects
Assessment
Exam
Resources
1. Industrial High Pressure Applications. Processes, Equipment and Safety / edited by R. Eggers. — Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. — 404 p. 2. Speight, James G.The Chemistry and Technology of Petroleum / J. G. Speight. — Fourth Edition. — New York: CRC Press, 2007. — 945 p. 3. Chemistry 1 / B. Ratcliff [и др.]. — Cambridge: Cambridge University Press, 2007. — 210 p. 4. http://www.sciencedirect.com
Professional English language. Higher Mathematics. Fundamentals of mechanics.
Course Objectives
Develop the ability to understand physico-chemical nature of the processes and to know the basic laws of chemical processes occurrence in complex production-technological activity. To know the basic design heat of equipment used in chemical industries. Develop the ability to perform the necessary physico-chemical and thermodynamic calculations of basic parameters of chemical-technological processes on the basis of methods, processes and apparatuses of chemical technology. The formation of creative thinking, the unification of fundamental knowledge of the basic laws and methods of calculation chemical processes and physico-chemical researches, with subsequent processing and analysis of research results. Formation of skills of independent theoretical and experimental research in the area of fundamental processes of chemical productions and chemical Cybernetics in the field of machines and apparatuses of chemical productions.
Learning Outcomes
Formation of knowledge about the basic processes of mass transfer and how to implement it in chemical technology. Training to skills of thematic information search. Formation of the basic skills of calculation of mass transfer processes in chemical engineering.
1. Examples and tasks by the course of processes and devices of chemical technology / Pavlov К.F., Romankov P.G., Noskov А.А. – L: Chemistry, 1987. – 576 p. (Russian). 2. Main processes and devices of chemical technology / Kasatkin A.G. – Moscow:TPH Aliance, 2004. – 753 p. (Russian).
Physics, Chemistry, Strength of Materials, Construction Materials Engineering
Course Objectives
This module gives an opportunity to review the breadth of materials science, to focus on some key ideas, and to reflect on its wider impact. The course is aimed at students training in: • research activity in the field of materials science; • industrial engineering and design activity in sphere of materials science and heat treatment; • self-study and development of new professional knowledge and abilities.
Learning Outcomes
Having successfully completed this module, you will know: • basic properties of up-to-date construction materials, • structure of materials, • ways of strengthening of structural materials. Having successfully completed this module, you will be able to: • choose a material and its processing for the specific purpose, • carry out metallographic analysis and standard tests for mechanical properties estimation, • interpret results of experiments, • specify time-temperature processing schedule, • search for the scientific and technical information in the field of materials science. Having successfully completed this module, you will aquire: • experience in research equipment operating, • skills in mechanical properties testing, • skills in phase diagrams analysis.
Syllabus
1. Materials’ structure and classification 2. Mechanical properties testing 3. Deformation and fracture of metals 4. Crystallization of metal 5. Structure of alloys 6. Iron and ferrous alloys 7. Heat treatment of steel 8. Nonferrous metals and alloys 9. Non-metallic constructional materials
Labs
1. Research technique in materials science. Metallographic analysis 2. Hardness testing 3. Plastic deformation, cold working and recrystallization 4. Crystallization 5. Microstructure of carbon steels and cast irons 6. Quenching and tempering of carbon steels 7. Heat treatment of aluminium alloys 8. Structure and properties of ceramics
Methods for testing operating characteristics of nanomaterials
Level of study
Master Degree
Workload
ECTS: 4 Total Hours: 144 Contact Hours: 48
Lectures: 8
Labs: 40
Seminars: 0
Course Code
М1.ВМ4.1.3
Semester
Winter
Prerequisites
• Modern problems of nanomaterials science • Solid-state physics • Inorganic chemistry
Course Objectives
The aim of the course is to provide students with methods for testing the performance characteristics of bulk materials and nanomaterials and learn to operate the modern equipment used for these purposes: corrosion properties, thermal properties
Learning Outcomes
Practical skills. Experience the definition of operational properties of materials and nanomaterials (thermal resistance, corrosion resistance) Intellectual skills. • Operate some equipment for study the kinetics of sintering, linear expansion coefficients • To determine the thermal properties of materials: CTE, shrinkage, sintering temperature, thermal effects of the materials. • Operate some equipment, for determination of electrochemical corrosion parameters: potentiostat, polarography. • Handle corrosive chart: to calculate corrosion potentials and currents; to describe electrolyte discharge processes, to determine the equilibrium potentials of some reductant and oxidant • Evaluate the corrosion resistance by means of gravity and microscopy methods
Syllabus
Section 1. Corrosion of nanomaterials 1.1 Classification of corrosion processes 1.2 micro-galvanic elements theory 1.3 Corrosion of nanomaterials 1.4 Some diagnostic techniques of corrosion properties 1.5 Ways of expressing the corrosion rate 1.6 General thermodynamics and kinetics 1.7 Anodic processes at the corrosion 1.8 Cathodic processes at the corrosion 1.9 Polarization curves 1.10 voltammetry Section 2. Thermal properties of nanomaterials 2.1 Thermal property: basics 2.2 Thermal property of nanomaterials 2.3 Dilatometry 2.4. Negative thermal expansion (NTE)
Labs
Lab 1. Practical work on voltammetry Lab 2. Corrosion of Nanostructured Titanium. Lab 3. Dilatometry of nanoceramics
Projects
● Nanomaterials for corrosion resistance ● Corrosion behavior of nanocrystalline material ● The protection of metals and alloys by nanomaterials ● Polymers coating for corrosion resistance
Assessment
Exam
Resources
1) Höhne G., Hemminger W.F., Flammersheim H.-J. Differential Scanning Calorimetry 2-nd ed. – Springer, 2003. – 298 p. 2) Wunderlich B. Thermal Analysis of Polymeric Materials – Springer, 2005. – 894 p. 3) Handbook of Thermal Analysis and Calorimetry, V. 3: Applications to Polymers and Plastics. – Elsevier, 2002. – 828 p. 4) Ehrenstein G.W., Riedel G., Trawiel P. Thermal Analysis of Plastics. Theory and Practice. – Hanser Gardner, 2004. – 396 p. 5) http://earthingservices.com/services/stray-current-corrosion-management/ 6) http://www.hitachi-rail.com/products/power_supply/equipment/feature04.html 7) Corrosion Continuing Education from the American Society of Plumbing Engineers. ASPE.ORG/ReadLearnEarn. 2014 8) X. G. ZHANG. GALVANIC CORROSION. Teck Metals Ltd., Mississauga, Ontario, Canada. Uhlig’s Corrosion Handbook, Third Edition, Edited by R. Winston Revie, 2011 John Wiley & Sons, Inc. P 123 – 144
Nanomaterials and environment: applications and risk assessment
Level of study
Master Degree
Workload
ECTS: 4 Total Hours: 144 Contact Hours: 48
Lectures: 8
Labs: 32
Seminars: 8
Course Code
М1.ВМ4.1.1
Semester
Winter
Prerequisites
• Modern problems of nanomaterials science and technologies; • Materials science and technologies of modern and advanced materials; • Polymeric and ceramic nanomaterials
Course Objectives
Module overview The aim of the course is to provide students with a multidisciplinary overview of engineered nanoparticles behavior in the environment in order to be able to critically estimate potential risks of nanomaterials in an occupational area Knowledge and understanding Deeply understand the mechanisms of nanoparticles interaction with environmental matrix considered on and informed by a multidisciplinary basis Intellectual skills Appraise environmental pollution incidents (origins, pathways and consequences) from an informed and scientific viewpoint Practical skills Evaluate the properties of nano-sized materials that influence their fate and impacts
Learning Outcomes
Knowledge and understanding. Having successfully completed the module, you should be able to demonstrate knowledge and understanding of: KU.1. content and structure of the course, including а также correlation of the course with other fields of natural science and materials science; KU.2. application fields of different nanomaterials in scientific, human and manufacturing sectors in presents and in the future; KU.3. industrial and lab-scale methods of nanomaterials synthesis as sources of nanoparticles release into the environment; KU.4. generic properties of nanomaterials and methods for its’ testing in environmental matrixes; KU.5. typical sources of nanoparticles release and mechanisms of nanoparticles migration in the environment, including atmosphere, hydrosphere, lithosphere and biosphere; KU.6. generic biological properties of nanomaterials. Intellectual skills. Having successfully completed the module, you will be able to: IS.1. classify nanomaterials according to its application and properties; IS.2. test structure and properties of nanomaterials in the environment; IS.3. use the internet critically as a source of information at studying nanomaterials risks; IS.4. appraise environmental pollution incidents (origins, pathways and consequences) at the using and production of nanomaterials; IS.5. classify nanomaterials according to their safety and interaction environmental matrixes, including occupational risks. Practical skills. Having successfully completed the module, you will be able to: PS.1. evaluate the properties of nano-sized materials that influence their fate and impacts; PS.2. elaborate approaches determining nanoparticles release, aggregation and sedimentation in the environment;v PS.3. work in team to analyze properly and solve the problem PS.4. synthesize the information into a coherent essay and write report and present information clearly.
Lab 1. Dispersity of nanopowders. Lab 2. Examination of nanomaterials surface with scanning probe microscopy: electrochemical preparation of probes. Lab 3.Examination of nanomaterials surface with scanning probe microscopy: tunneling probe and atomic force microscopy. Lab 4. Sedimentation analysis of nanopowders. Lab 5. Estimation and prognosis of dissolution rate and dissolution degree of metal nanoparticles solubility in simulating body fluids Lab 6. Dispersion analysis of nanoparticles suspensions with laser diffraction method
Projects
● Shape-dependent ecotoxicity of nanoparticles ● Influence of nanoparticles concentration on ecotoxicity ● Size-dependent toxicity of nanoparticles ● Charge-dependent ecotoxicity of nanoparticles ● Influence of metal nanoparticles solibility on ecotoxicity ● pH-dependent ecotoxicity of nanoparticles ● Influence of water salinity on ecotoxicity of nanoparticles ● Influence of stabilization on lethal doses of nanoparticles ● Influence of morphology on ecotoxicity of carbon nanotubes ● Size-dependent ecotoxicity of fullerene nanoparticles ● Size-dependent ecotoxicity of nanoparticles ● Influence of impurities on toxicity of nanoparticles
Assessment
Exam
Resources
Recommended supporting on-line tutor’s materials LMS Moodle http://stud.lms.tpu.ru/course/view.php?id=18 Web-page of the tutor https://portal.tpu.ru/SHARED/g/GODYMCHUK Primary literature: 1. Buzea C., Pacheco I., Robbie K. Nanomaterials and nanoparticles: Sources and toxicity, USA: American Vacuum Society. – 2007. – 65 p. 2. Karlsson H.L. The comet assay in nanotoxicology research // Analitical and Bioanalitical Chemistry. – 2010. – Vol.398. – P.651-666 3. Nanomaterials: a risk to a health? // Proceedings of the First International Symposium on Occupational Health Implications of Тanomaterials, 12-14 October 2004, Palace Hotel, Buxton, Derbyshire, UK. [Электронный ресурс]:http://www.hsl.gov.uk/capabilities/nanosymrep_final.pdf 4. Warren H. Hunt. Nanomaterials: Nomenclature, Novelty, and Necessity // Journal of the Minerals, Metals and Materials Society. – 2004. – Vol. 56. – No. 10. – P. 13-18. 5. Piccinno F., Gottschalk F., Seeger S., Nowack B. Industrial production quantities and uses of ten engineered nanomaterials for Europe and the world // Journal of Nanoparticles Research. – 2012. – Vol.14. – P.1109-1120. 6. G. Oberdörster, E. Oberdörster, and J. Oberdörster “Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles” // Environmental Health Perspectives. 2005 – Vol.113. – P.823-839. Supplementary literature: 1. Woodrow Wilson Center Project on Emerging Nanotechnologies, Inventory of Consumer Products. 2006. [Электронный ресурс]: http://www.nanotechproject.org/44. 2. National Nanotechnology Initiative: leading to the next industrial revolution. A Rep. by Interagency Working Group on Nanoscience, Engineering and Technology. Committee on Technology of Nat.Sci. and Techn. Council, USA, Washington D.C., Feb. 2000. 3. U.S. Department of Agriculture. 2003. Nanoscale Science and Engineering for Agriculture and Food Systems. Report Submitted to Cooperative State Research, Education, and Extension Service. Norman Scott (Cornell University) and Hongda Chen (CSREES/USDA) Co-chairs. 4. Andrievsky G.V., Burenin I.S. Hydrated C60 Fullerenes as Versatile Bio-Antioxidants, which in Biological Systems Regulate Free-Radical Processes by the "Wise” Manner. Proc.of Nanofair Conf. 2004, September 14-16, 2004, St. Gallen, Switzerland, №261[Электронный ресурс]: (http://www.nanofair.ch). 5. Klaine S.J., Alvarez P.J.J., Batley G.E., Fernandes T.F., Handy R.D., Lyon D.Y., Mahendra S., McLaughlin M.J., Lead J.R. Nanomaterials in the environment: behavior, fate, bioavailability, and effects // Environ Toxicol Chem. – 2008. – Vol. 27(9). – P. 1825–1851. 6. Oberdorster G., Stone V., Donaldson K. Toxicology of nanoparticles: a historical perspective // Nanotoxicology. – 2007. – Vol. 1. P. 2–25. 7. Pettitt M.E., Lea J.R. Minimum physicochemical characterisation requirements for nanomaterial regulation // Environment International. – 2013. – Vol.52. – P.41-50. 8. Buffle J. The key role of environmental colloids of nanoparticles for sustainability of life // Environment and Chemistry. – 2006. – Vol.3. – P.155-158. 9. Farre M., Gajda-Schrantz K., Kantiani L., Barcelo D. Ecotoxicity and analysis of nanomaterials in the aquatic environment // Analytical and Bioanalytical Chemistry. – 2009. V.393. – P.81-95. Internet resources: 1) Database Elsiver (free access with TPU’s account): http://www.sciencedirect.com/ 2) Database Springer (free access with TPU’s account): http://www.springerlink.com/ 3) Database WorldScientific (free access with TPU’s account): http://www.worldscientific.com 4) Database Tom Hill Dovepress (free access with TPU’s account): http://www.dovepress.com/ 5) Database RCS Publishing (free access with TPU’s account): http://pubs.rsc.org/ 6) Database PubMed (free access with TPU’s account): http://www.ncbi.nlm.nih.gov/pubmed 7) Database Scientific Research (free access with TPU’s account): http://www.scirp.org/journal/OpenAccess.aspx 8) Database ACS Publications: http://pubs.acs.org/ 9) Database CSIRO Publishing: http://www.publish.csiro.au/home.htm 10) Database Oxford Journals: http://www.oxfordjournals.org/
The students will: • recognize main functional groups of organic compounds and predict their chemical properties, taking into account the type of chemical bond connectivity, hybridization state, and stereochemistry; • identify reaction mechanisms for chemical processes with formation of intermediate free radicals, nucleophilic, and electrophilic agents; predict major product in reactions with participation of organic compounds; • define the reagent nature as free radical, nucleophilic, or electrophilic, and use this knowledge to perform a synthesis of organic compounds belonging to main classes; • demonstrate laboratory skills, including safety, handling and disposal of organic compounds; experimental procedures such as isolation, purification and structure identification of reaction products obtained; use of laboratory equipment; and writing experimental reports according to the style adopted for scientific publications
Learning Outcomes
Upon completion of this module the students will be able to • develop an optimum procedure for obtaining specified organic compounds from commercially available initial substances; • make identification of organic compounds on the base of their nuclear magnetic resonance (NMR), infra-red (IR), and mass spectra; • predict direction of a chemical processes with a participation of organic compounds regarding possible reaction mechanisms; • suggest methods of isolation and identification of synthesized organic compounds belonging to different classes.
Syllabus
Introduction. Classification of organic compounds. Classification of organic reactions and reagents. Alkanes, alkenes, and alkynes: obtaining and chemical properties. Arenes: aromaticity, structure, isomerism, nomenclature, and obtaining. Orientation rules in the aromatic ring. Electronic effects in organic molecules. Halogen derivatives of hydrocarbons: obtaining and properties. Alcohols and phenols: obtaining and chemical properties. Carbonyl compounds: aldehydes and ketones. Carboxylic acids and their derivatives. Nitrogen-containing compounds: nitroarenes and nitroalkanes, amines
Labs
Simple distillation of organic solvents. Thin-layer chromatography and its application for reaction control. Synthesis of propylene. Purification of p-nitrobromobenzene. Synthesis of isopropyl bromide.
Projects
Assessment
Quiz: Classification of organic reactions. Quiz: Halogen derivatives. Quiz: Alcohols and phenols. Quiz: Carbonyl compounds and amines. Final assessment: Exam
Resources
• Organic Chemistry Paula Y. Bruice Hardcover, 1440 Pages 6th Edition, 2010 ISBN: 978-0-321-66313-9 Prentice Hall • http://www.organic-chemistry.org • http://www.reaxys.com
Giving the theoretical and experimental basis of spectral methods which are used for elucidation of organic compounds structure.
Learning Outcomes
• To develop skills in elucidation of molecular structure using modern spectroscopic instrumentations • To apply knowledge of chemical and physical principles of spectroscopic techniques to the solution of qualitative and quantitative chemical problems • To be able to read and critically evaluate the chemical and scientific literature • To be able to find information and spectral data of substances in spectroscopic databases • To learn to present scientific data clearly and effectively through both written and verbal communication
Syllabus
UV and visible spectroscopy, chromophores and auxochromes, qualitative and quantitative analysis by UV spectroscopy. IR spectroscopy, vibrational spectra, sample preparation. NMR spectroscopy, proton magnetic resonance, chemical shifts, spin-spin coupling, multiplets 13C resonance,2D NMR spectroscopy . Mass Spectrometry, EI mass fragmentation, determination of molecular ion, using the techniques to the elucidate the molecular structures.
Labs
1 Spectral databases and specialized software for modeling and illustration chemical formulae and spectra. 2 Determination of concentration of organic substance by electron spectroscopy. 3 Measuring and modeling IR spectra of chemical substance with HyperChem Pro 6. 4 Moldeing NMR 1Н and 13C using ACD Labs (CNMR, HNMR) and Chem Draw Ultra 9. 5 Structural analysis of organic substance using EI Mass-spectrometry
Projects
Structure elucidation of selected organic substance by using all known spectral methods.
Assessment
Exam
Resources
1. Silverstein R. M., Webster F.X. Spectrometric Identification of Organic Compounds 2. Field, L. D., Sternhell, S., Kalman J. R. Organic Structures from Spectra, 5th Edition 3. AIST database http://sdbs.db.aist.go.jp/sdbs/cgi-bin/cre_index.cgi 4. NIST database http://webbook.nist.gov/ 5. BMRB database http://www.bmrb.wisc.edu/metabolomics/db_ find/index.php
Technologies to manufacture bulk nanostructured materials
Level of study
Master Degree
Workload
ECTS: 6 Total Hours: 216 Contact Hours: 64
Lectures: 32
Labs: 32
Seminars: 0
Course Code
М1.ВМ4.1.2
Semester
Winter
Prerequisites
Materials science. Powder technology.
Course Objectives
1. Understanding the problems of consolidation of bulk nanostructured materials. 2. Insight of methods of compaction, shaping, sintering of powders regarding nanopowder peculiarities. 3. Nanostructure impact at application of functional ceramics and composites.
Learning Outcomes
After completing the course the student will be able to: – determine the compaction equations and compaction curves of dry powders – calculate the parameters of powder compaction - characterize the methods of compaction, shaping, sintering of powders – choose the technology for shaping and consolidation of specific parts from nanoceramics/nanocomposites
Syllabus
1. Introduction, basics of powder processing 2. Bulk nanostructured materials: classifications, types, consolidation problems. 3. Methods of powder compaction and shaping 3.1. Uniaxial pressing (static, dynamic) 3.2. Compaction equations, compaction curves 3.3. Kinds of dynamic compaction; magnetic pulsed compaction; explosive compaction 3.4. Isostatic pressing 3.5 Rolling 4. Dry powder compaction using Powerful Ultrasound Assistance (PUA) and by the “Collector Pressing” 5. Methods of sintering, consolidation 5.1. Sintering Measurement Techniques 5.2. Classic Models of Sintering 5.3. Grain Growth in Sintering 5.4. Sintering using pressure: hot pressing; spark plasma sintering 5.5. Field-assisted consolidation. 5.6. Combination of rolling and sintering 5.7. Slip casting 6. Functional ceramics and composites 6.1. Conductors, superconductors, semiconductors, dielectrics. Nanostructure impact. 6.2. Transparent ceramics 6.3. Carbide ceramics 6.4. Metal-ceramic composites
Labs
1 Spark plasma sintering 2. SEM / TEM 3. Porosimetry, BET analysis
Projects
Assessment
Exam
Resources
1. Handbook of Advanced Ceramics. Editor S.Somiya. 2nd edition // Elsevier Academic Press, 2013, 1229 p. 2. Nanomaterials. Handbook. Editor Y.Gogotsi // CRC Press, 2006, 780 p. 3. S.J. Kang. Sintering: Densification, Grain Growth and Microstructure // Elsevier, 2005, 265 p. 4. Хасанов О.Л., Двилис Э.С., Бикбаева З.Г., Качаев А.А., Полисадова В.В. Методы компактирования и консолидации наноструктурных материалов и изделий // М.: БИНОМ. Лаборатория знаний, 2013, 269 с.
Professional English language. Processes and devices of chemical technology. The main directions of the chemical technology of inorganic substances.
Course Objectives
Formation of the ability to operate and service modern high-tech production of mineral; fertilizers, to correspond the environmental protection requirements and the rules of industrial safety.
Learning Outcomes
Master students will be able to: discuss the basic technologies of fertilizers; select the raw materials and technology for producing the fertilizers; control the quality of raw materials and products; apply the professional knowledge and skills in the field of chemical technology of fertilizers; predict the environmental impact of the technological scheme of fertilizer manufacturing.
Syllabus
• Types of mineral fertilizer, their role in plant life • The world market for mineral fertilizers • The main processes and devices in fertilizer technology • One-component fertilizers • Multi-component fertilizers • Impact the fertilizer on the environment
Labs
Projects
• Main advantages & disadvantages of different types of fertilizers. • Global trends in the production of mineral fertilizers. • Typical equipment for basic processes in the fertilizer manufacturing. • Global trends in the production of mineral single-component and multi-component fertilizers. • Methods for effective utilization of the wastes of fertilizer manufacturing.
Assessment
Credit Test
Resources
1. Havlin J.L., Tisdale S.L., Nelson W.L., Beaton J.D. Soil Fertility and Fertilizers: An Introduction to Nutrient Management. 7th Edition. – Prentice Hall. 2005. – 528 p. 2. The Complete Technology Book on Minerals and Mineral Processing. By NPCS Board of Consultants and Engineers. – National institute of industrial research. 2008. 3. Ross J.R.H. Heterogeneous Catalysis: Fundamentals and Applications. – Elsevier. 2011. – 232 p. 4. Evangelou V. P. Pyrite Oxidation and its Control. CRC Press, 1995. – 293 p. 5. Palgrave D.A. Fluid Fertilizer Science and Technology. – CRC Press. 1991. – 648 p. 6. Marisa Callio, Ana Gimeno, David Perry, Rafael Seiz. English for Mechanical and Chemical Engineering. – Reproval S.L. 2001. – 132 p. Internet-resources 1. Fertilizers and their use: ftp://ftp.fao.org/agl/agll/docs/fertuse.pdf 2. Nitrogen cycle in the soil: https://www.youtube.com/watch?v=Ekx84-T5GLk 3. Chemical Engineering. Fertilizer Technology: http://www.indiabix.com/chemical-engineering/fertiliser-technology/
Theoretical Foundations of energy and resource saving
Level of study
Master Degree
Workload
ECTS: 3 Total Hours: 108 Contact Hours: 48
Lectures: 8
Labs: 0
Seminars: 40
Course Code
Semester
Summer
Prerequisites
Basic processes and equipment of chemical plants. Modelling of technological and natural systems.
Course Objectives
Forming depth knowledges of physical and chemical nature of energy and resource saving processes and subsequent analysis of the results. Formation at students of scientific and engineering approach to the rational use of energy- and material resources, in chemical engineering, petrochemical and biotechnology. Apply the theoretical and technological bases for the energy- and resource saving processes in the analysis and evaluation of the effectiveness of chemical-technological processes.
Learning Outcomes
Apply the deep mathematical, scientific, socio-economic and professional knowledge in the field of energy-and resource-saving processes of the technology of chemical, petrochemical and biotechnology in the professional activity. Develop a new technological processes based on mathematical modeling, design and use of energy and resource saving equipment of chemical technology, petrochemical and biotechnology. Carry out theoretical and experimental research in the development and optimization of technological processes and systems from the standpoint of saving energy and resources.
Syllabus
• Problems of energy and resource saving technologies in the chemical, petrochemical, biotechnology. • Thermodynamic analysis of chemical-technological industries and chemical processes. • System analysis of the main methods of energy saving and resource saving technologies in the chemical, petrochemical and biotechnology. • The use of secondary energy resources in the chemical industry. • Power Technologies of large tonnage productions.
Labs
1. Comparative analysis of technological schemes. 2. Thermodynamic analysis and evaluation of the degree of perfection of chemical industries. 3. Calculation of the energy balance of flows of chemical production. 4. Analysis of the distillation or heat exchange process. 5. The thermodynamic analysis of the of fuel combustion; 6. Analysis of the pyrolysis process.
Projects
Assessment
Credit Test
Resources
1. Лейтес И.Л., Сосна М.Х., Семенов В.П. Теория и практика химической энерготехнологии.- М.: Химия, 1988. 280 с. 2. Сажин Б.С., Булеков А.П. Эксергетический метод в химической технологии. - М.:-Химия,1992. 208 с. 3. Основы проектирования химических производств и оборудования Учеб. пособие./ В.И. Косинцев и др. - Томск: Изд. ТПУ, 2011. 397 с. 4. С. Бретшнайдер и др. Общие основы химической технологии. Разработка и проектирование технологических процессов. - Л.: Химия, 1977. 580 с. 5. Бродянский В.М., Фратшер В.. Михалек К. Эксергетический метод и его приложения. - М.: Энергоатомиздат, 1988. 201 с. 6. Степанов В.С., Степанова Т.Б. Потенциал и резервы энергосбережения в промышленности. - /Новосибирск.: Наука, 1990. 248 с. 7. Степанов В.С., Степанова Т.Б. Эффективность использования энергии. - Новосибирск.: ВО Наука, Сиб. изд. фирма, 1994. 257 с. 8. Бескоровайный, В.В. Теоретические основы энерго- и ресурсосбережения: учебное пособие/ В.В. Бескоровайный, А.Г. Фомичев, В.В. Шелгунов. Изд.1–е. Тверь: ТГТУ, 2009. 96 с. 9. Меркер Э.Э., Карпенко Г.А., Тынников И.М. Энергосбережение в промышленности и эксергетический анализ технологических процессов: Учебное пособие.–2-е изд.,перераб. И доп.– Старый Оскол: ООО «ТНТ», 2007. 316 с.
