prognosis of cancer outcome and cancer therapy efficiency;,
immunological mechanisms (checkpoints) as targets for cancer therapy. Participation in research projects:
2000 – 2003. “Immunological mechanisms of biological response modifiers used in patients with oncological and preoncological disorders”.
2005. “Adjuvant chemotherapy combined with immunotherapy during cancer treatment of local gastric cancer”.
2002 - 2007. “Research of role of immunogenetic factors of anticancerogenesis at tumor growth stages and during therapy by modifiers of biological response”.
2004 – 2011. “Pro- and anti-tumor aspects of participation of immune system in breast cancer pathogenesis during combined cancer treatment”.
2005. “Study of role of immunogenetic mechanisms (polymorphism of p53 and CCR5 genes) in pathogenesis, clinical course and cancer treatment efficiency in lung cancer patients”.
2005 – 2008. “Influence of Xenon anesthesia on adaptation reactions during surgical treatment of breast malignant tumors”.
2005-2009. “Improvement of endogenous artificial limbs’ technics by using of modern computer technologies”.
2006 - 2008. Integrated project of Siberian branch of Russian Academy of Medical Sciences “Molecular-genetic mechanisms of breast cancer formation and progression: elaboration of criteria of formation hazard, outcome and chemotherapy sensitiveness prognosis based on revealing of informative markers of tumor and host”.
2007 - 2009. “Xenon anesthesia during combined treatment in patients with cancer of larynx”.
2012 -2015. “Experimental studying of stem cells phenotype”.
2012-2015. “Research of population rules and molecular-genetic mechanisms of malignant tumors formation and progression in Siberian people”.
2014 up to now. “Basing of use novel cell and molecular factors of immune system for prognosis of breast cancer hematogenous metastases”. Skills and abilities:
Basic immunological methods, particularly methods of cell culturing in vitro.
Certificated specialist of flow cytometery.
Experience of working in large data statistics, particularly, unique skills in working in multidimension data visualization soft NovoSpark Visualizer. Achievements:
1993. Defence of thesis “The role of drugs from Hyppophae rhamnoides in regulation of natural resistance system in normal and oncological conditions”, conferment of PhD.
2011. Defence of thesis “The role of immune system in breast cancer pathogenesis during anticancer treatment”, conferment of MD.
2 patents RU:
"Remedy obtained of adaptogene activity and mode of premedicating of breast cancer patients to specific cancer treatment included polychemotherapy”,
“Mode of breast cancer hematogenous metastases prognosis based on estimation of immune system state during cancer treatment”.
Medical technology “Monitoring of hematogenous metastases hazard in breast cancer patients based on estimation of immune system state during cancer treatment”.
Diploma I degree of invest session «Bridge to success»of Innovation Forum Innovus in Tomsk for project “Creation of soft for malignant tumor prognosis”, 2011.